Research

Unfortunately, current treatments for macular degeneration are limited. While we can often limit vision loss, after treatment we usually are left with some damage to the vision. We usually cannot recover vision damaged prior to the treatment. Furthermore, there are many patients who are not candidates for the standard laser treatment. Because our treatment options are limited, extensive research is underway in this area. Current clinical research trials at Illinois Retina Associates related to macular degeneration are summarized here:

-Age Related Eye Diseases Study (AREDS).
This National Eye Institute-sponsored study is examining the role of vitamin supplements in reducing the risk of progression of macular degeneration. Patients are randomly assigned to take either very high doses of antioxidant vitamins and minerals or a regular multivitamin tablet.

-Complication of ARMD Prevention Trial (CAPT).
The National Eye Institute is sponsoring this study evaluating the potential for early laser treatment to reduce the risk of progression from dry to wet macular degeneration. Patients with many drusen in both eyes and good vision in both eyes receive laser treatment to one eye. A light laser treatment is applied to treat the drusen. The CAPT is currently accepting new patients.

-Submacular Surgery Trials (SST).
This National Eye Institute-sponsored study is assessing surgery to remove the blood and abnormal blood vessels from beneath the retina. Patients with wet macular degeneration are randomly assigned to either a surgery group or an observation group. Patients are eligible for this study only if they do not meet MPS criteria for standard laser treatment. The SST is currently accepting new patients.

-Ocular Photodynamic Therapy (OPT).
This industry sponsored trial is testing a new type of laser treatment for macular degeneration. A photosensitive dye is injected prior to laser treatment. The dye accumulates in the abnormal blood vessels, making them more sensitive to laser treatment. A much lower laser energy is then used to treat the area. This low-power laser typically does not result in a blind spot in the area of treatment. Patients often need to be retreated at three-month intervals.