Mathew MacCumber, MD, PhD, FASRS

Mathew MacCumber, MD, PhD, FASRS

“Other doctors in the group have a lot of experience in developing instruments. My research training in neuropharmacology is a good fit because the next frontier is the applications of new medicines to the mechanics of eye surgery. At Illinois Retina, we combine research and clinical research studies with patient care to push the edge of medicine.”

Mathew W. MacCumber, MD, PhD, is a nationally recognized expert in the medical and surgical treatment of vitreoretinal disease. He completed his undergraduate studies at Princeton University. He earned his medical degree and PhD, in neurosciences, at the Johns Hopkins University School of Medicine, and served as the Assistant Chief of Service at the Wilmer Eye Institute, at Johns Hopkins. He received the prestigious Ronald G. Michels Fellowship, which lead to his retina training at Duke University Eye Center.

In 1996, Dr. MacCumber joined Illinois Retina Associates and Rush University Medical Center, where he now holds the positions Professor and Director of Research for the Department of Ophthalmology.   He sees patients in our Oak Park, Rush University Medical Center and Lincoln Park office locations.

Dr. MacCumber is an active participant in national and local ophthalmic associations. He was Chair of the American Academy of Ophthalmology (AAO) Council, as well as a member of the AAO Board of Trustees.  He has served on the Board of Directors of the Macular Society and the American Society of Retina Specialists (ASRS), and is a Past-President of the Chicago Ophthalmological Society. He currently serves on the board of the Illinois Society for the Prevention of Blindness.

Dr. MacCumber directed the Vitreoretinal Fellowship program at Rush University Medical Center and Illinois Retina Associates for 8 years. He has received the AAO Achievement Award, the AAO Senior Achievement Award, the ASRS Senior Award, as well as two Secretariat Awards from the AAO for Education and Advocacy.

He authored or co-authored 44 peer-reviewed articles, 172 total articles, 11 book chapters, and he edited the text Management of Ocular Injuries and Emergencies. Dr. MacCumber is a frequent speaker nationally and internationally, and has served as Principal Investigator for more than 25 multicenter clinical trials. He currently serves on the executive committee of the DRCR Retina Network and co-chairs the National Eye Institute-funded multi-center “Randomized Trial Comparing Immediate versus Deferred Surgery for Symptomatic Epiretinal Membranes.

Dr. MacCumber lives in Chicago with his wife, Judith Weinstein, MA, MPH.  Their daughter, Abigail, lives in Los Angeles, their son, David, in Chicago and son, Ethan, in New York City.   In his free time, Dr. MacCumber enjoys tennis, biking, skiing and spending time with his family.

Dr. Mathew MacCumber’s Patient Testimonial

Clinical Trials/Research Studies

  • Principal Investigator, Longitudinal Study of the Ocular Complications of AIDS (L-SOCA)
  • Principal Investigator, Submacular Surgery Trials
  • Principal Investigator, Vitrectomy for Diffuse Diabetic Macular Edema
  • Principal Investigator, Diabetic Retinopathy Clinical Research Network
  • Principal Investigator, Safety Assessment of Intravitreal Lucentis for AMD (SAILOR and HARBOR)
  • Investigator, ThromboGenics Study

Articles in the Following Scientific Journals

  • Archives of Ophthalmology
  • Retina
  • Ophthalmology
  • Journal of Neuroscience
  • Proceedings of the National Academy of Sciences
  • Science

Societies and Organizations

  • American Society of Retina Specialists, board member 2010-present
  • Macula Society, board member 2009-present
  • Chicago Ophthalmological Society, annual meeting program director, 2002; board member 2008-present
  • American Academy of Ophthalmology, councilor, 2010-present
  • Retina Society
  • Illinois Association of Ophthalmology
  • Association for Research in Vision and Ophthalmology
  • American Medical Association
  • American Academy of Ophthalmology
  • American Society of Retina Specialists

Chief Residency

  • Ophthalmology – The Wilmer Ophthalmological Institute, Johns Hopkins Hospital


  • Retinal Specialist – The Duke University Eye Center


  • Ophthalmology – The Wilmer Ophthalmological Institute, Johns Hopkins Hospital


  • Franklin Square
  • Hospital Center

Doctoral Degree

  • Ph.D. – Johns Hopkins University School of Medicine

Medical School

  • M.D. – The Johns Hopkins University School of Medicine


  • B.A. – Princeton University